15th International Conference
on Drosophila Heterochromatin

Gubbio, Italy • 9-15 June 2024

15th International Conference
on Drosophila Heterochromatin

Gubbio, Italy • 9-15 June 2024

15th International Conference
on Drosophila Heterochromatin

Gubbio, Italy • 9-15 June 2024

Programme

Sunday, 9 June 2024

18:00

Registration and Welcome cocktail (apericena) at Bosone Garden (Via della porta, Gubbio)

Monday, 10 June 2024

9:00-9:30

Registration, welcome and opening of the meeting

Chair: Barbara Wakimoto

9:30-10:00

Igor Sharakhov
Developmental dynamics of the chromatin architecture in the malaria mosquito

10:10-10:40

Maria Sharakhova
Heterochromatin expansion in the mosquito genomes by transposable element activities

10:50-11:10

Coffee break

11:10-11:40

Argandita Meiftasari
Histone H4 variant (His4r) is a novel Su(var) gene regulating heterochromatin establishment in early development of Drosophila melanogaster

11:50-12:20

Katalin Fejes Toth
Beyond the histone code: an unexpected function of SetDB1 in heterochromatin spreading and maintenance

12:30-13:00

Emmanuel Gonzalez Sqalli
Functional analysis of the histone variant macroH2A in the cricket Gryllus bimaculatus

13:10-14:30

Lunch

14:30-15:00

Victoria Meller
X marks the spot, but heterochromatin calls the shots

15:10-15:40

Lori Wallrath
Journey from the nuclear envelope back to heterochromatin

15:50-16:20

Pamela Geyer
Centrosome dysfunction contributes to stem cell loss in a nuclear lamina mutant

16:30

Visit to the medieval town of Gubbio and “panoramic” dinner

Tuesday, 11 June 2024

Chair: Lori Wallrath

9:00-9:30

Prim Singh
HP1-driven phase separation: an in vitro artefact or an in vivo organizing principle?

9:40-10:10

Derek Atkinson
JASPer is a novel Su(var) factor that regulates transcription of the white gene and pericentric satellite repeats

10:20-10:50

Alexei Aravin
A battle between canonical and non-canonical transcription in the piRNA pathway

11:00-11:20

Coffee break

11:20-11:50

Yang Yu
RNA polymerase II stalling facilitates termination and piRNA-guided heterochromatin formation

12:00-12:30

Maria Ninova
SUMOylation “hot spots” in Drosophila heterochromatin and transposon silencing pathways revealed by diGly proteomics

12:40-13:10

Tatyana Kolesnikova
Otu and Rif1 double mutant enables analysis of satellite DNA and piRNA clusters  in polytene chromosomes of ovarian germ cells in Drosophila melanogaster

13:20-15:00

Lunch

15:00-15:30

Kevin Wei
Suppression of recently expanded retroelements through restricted H3K9me3 nucleation during embryogenesis in Drosophila miranda

15:40-16:10

Maria Pia Bozzetti
Investigating the role of transposable elements during development of the Drosophila melanogaster nervous system under normal and stressful conditions

16:20

Poster Session and coffee break

  • List of Posters

    Ho-Chen Lin
    Mechanisms of ring chromosome lethality

    Jeff Sekelsky
    Karyotype engineering to assay effects of heterochromatin on meiotic recombination

    Nila Pazhayam
    Centromere-proximal crossover suppression: genetic or structural?

    Jie Wang
    A novel factor essential for transcription within Drosophila heterochromatin

    Inés Hernández Crego
    Dissecting dosage-compensation systems in Drosophila ananassae using CRISPR/Cas9-induced homology directed repair

    Matthew Nalley
    Dynamic gene content evolution on the Drosophila Y chromosome

    Katherine Lemons
    Maintenance of genomic integrity in the male germline of Drosophila melanogaster

    Qiu Peng
    Drosophila Amus and Bin3 methylases functionally replace mammalian MePCE for capping and the stabilization of U6 and 7SK snRNAs

    Zhang Ting
    Angel Wing is an ancient class of alternative splicing regulators important for neuro- and muscular-developments

    William Sullivan
    Ubiquitous ultrafine connections between sister and non-sister telomeres of segregating chromatids maintain euploidy

    Min Cui
    The function of telomere capping protein HipHop in regulating telomeric transposon transcription and transposition in Drosophila

20:00

Free time for dinner (not included in the package)

Wednesday, 12 June 2024

Chair: Maurizio Gatti

9:00-9:30

Yikang Rong
The Ptch methylase installs an m3U modification on 28S rRNA for efficient protein synthesis in flies and men

9:40-10:10

Keith Maggert
Insights into ribosomal DNA (rDNA) dominance and magnification

10:20-10:40

Coffee break

10:40-11:10

Mia Levine
Rapid protein coevolution preserves the establishment and maintenance of telomere protection

11:20-11:50

Brandt Warecki
Ubiquitous connections between the telomeres and subtelomeres of segregating chromosomes aid in maintaining euploidy

12:00-14:00

Lunch

14:00

Departure to visit Perugia

Thursday, 13 June 2024

Chair: Keith Maggert

10:00-10:30

Amanda Larracuente
Rapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila

10:40-11:10

Jan Larsson
Painting of fourth interacts with CENP-C and is involved in chromosome segregation

11:20-11:40

Coffee break

11:40-12:10

Priscila Santa Rosa
Histone 4 lysine 20 mutation elevates mitotic recombination in heterochromatic regions in Drosophila melanogaster

12:20-12:50

Kent Golic
Mechanisms of mitotic pairing in Drosophila melanogaster

13:00-15:00

Lunch

Chair: Pamela Geyer

15:00-15:30

James Baldwin-Brown
Chromosome pairing loss in Drosophila hybrids

15:40-16:10

Maurizio Gatti
Replication stress and heterochromatin stability in Drosophila

16:20-16:50

Hunter Hill
Dicentric chromosomes display unique breakage patterns based on centromere origin

17:00-17:20

Coffee break

17:20-17:50

Alison Mills
Bridging broken bonds: exploring a role for ultrafine DNA bridges in preserving genomic integrity

18:00-18:30

Marieke Wensveen
Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

18:40-19:10

Wolfgang Miller
To kill or not to kill: evolutionary long-term relationships with facultative Male-Killing Spiroplasma in neotropical Drosophila flies

19:20

Free time for dinner (not included in the package)

Friday, 14 June 2024

Chair: Kent Golic

9:00-9:30

Arthur Hilliker
A genetic map of the heterochromatin of the major autosomes

9:40-10:10

Patrizio Dimitri
Drosophila melanogaster heterochromatic genes controlling different steps of the cell-cycle

10:20-10:50

Doris Bachtrog
Dynamic gene content evolution on Drosophila Y chromosomes

11:00-11:20

Coffee break

11:20-11:50

James Birchler
The inverse effect through the phyla and the implications for dosage compensation of the Drosophila X chromosome

12:00-12:30

Cara Brand
Intra-genomic coevolution between a DNA satellite and Topoisomerase II triggers an inter-species incompatibility

12:40-13:10

Ching-Ho Chang
Genetic conflicts shape rapid evolution of young Drosophila protamines

13:20-15:00

Lunch break

Chair: William Sullivan

15:00-15:30

Jackson Bladen
The speed and complexity of the evolutionary arms race of a Sex-Ratio chromosome

15:40-16:10

Cécile Courret
SR drive and the evolutionary history of the Y chromosome in Drosophila simulans

16:20-16:50

Jackson Ridges
Overdrive is essential for targeted sperm elimination by Segregation Distorter

17:00-17:20

Coffee break

17:30-18:00

Raphaelle Dubruille
Establishing paternal chromosome identity in the Drosophila male germline Katalin

18:10-18:40

Helen Salz
An X-linked heterochromatin mini-domain stabilizes female germ cell identity

20:00

Farewell Banquet in Gubbio!

Saturday, 15 June 2024

Breakfast and departure